This guide is for the original (2014) release of Ishin. The information contained within may not necessarily be accurate for the 2023 "Like a Dragon: Ishin" remake.
1
Recover the Stolen Money Boxes #1

You can do this after completing all the Thieves' Mine missions
Objective: Find all the money boxes (indicated on the map above with red dots), then defeat the mini-boss. You cannot enter the final room until you have found all the money boxes.
Difficulty: ***** || Reward: 3 Ryo
Obtainable Items:
Dragon Fang || Samurai's Hair String || Straw Figure || Water God Stone || Flint || Black Obi || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth
2
Recover the Stolen Money Boxes #2

You can do this after completing Mission 1
Objective: Find all the money boxes (indicated on the map above with red dots), then defeat the mini-boss. You cannot enter the final room until you have found all the money boxes.
Difficulty: ****** || Reward: 3 Ryo
Obtainable Items:
Dragon Whisker || Murderer's Handcuffs || Folding Fan || Bloodstained Cloth || Indigo Stone || Golden Stamp || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder || Gold Metal Powder
3
Recover the Stolen Money Boxes #3

You can do this after completing Mission 2
Objective: Find all the money boxes (indicated on the map above with red dots), then defeat the mini-boss. You cannot enter the final room until you have found all the money boxes.
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Dragon Eye || Sultry Doll || Dragon Tear || Crystal || Fenghuang Feather || Ancient Amulet || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder
4
Rescue the Kidnapped Villagers #1

You can do this after completing all the Thieves' Mine missions
Objective: Defeat the mini-boss, then talk to the kidnapped villagers.
Difficulty: ***** || Reward: 3 Ryo
Obtainable Items:
Dragon Fang || Samurai's Hair String || Straw Figure || Water God Stone || Flint || Black Obi || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-coloured Fragment || Precision Machine || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-coloured Fabric || Silver Metal Powder || Gold Metal Powder
5
Rescue the Kidnapped Villagers #2

You can do this after completing mission 4
Objective: Defeat the mini-boss, then talk to the kidnapped villagers.
Difficulty: ****** || Reward: 3 Ryo
Obtainable Items:
Dragon Eye || Sultry Doll || Dragon Tear || Crystal || Fenghuang Feather || Ancient Amulet || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth
6
Rescue the Kidnapped Villagers #3

You can do this after completing mission 5
Objective: Defeat the mini-boss, then talk to the kidnapped villagers.
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Crimson Jewel || Murderer's Handcuffs || Folding Fan || Bloodstained Cloth || Indigo Stone || Golden Stamp || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder
7
Attack Soldier Training

You can do this after completing all the Thieves' Mine missions
You can only play this mission with a squad of ONLY Attack soldiers
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Dragon Eye || Sultry Doll | |Dragon Tear || Crystal || Fenghuang Feather || Ancient Amulet || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder || Gold Metal Powder
8
Defence Soldier Training

You can do this after completing mission 7
You can only play this mission with a squad of ONLY Defence soldiers
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Snake Skin || Samurai's Hair String || Straw Figure || Water God Stone || Flint || Black Obi || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder
9
Medical Soldier Training

You can do this after completing mission 8
You can only play this mission with a squad of ONLY Medical soldiers
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
God Slaying Talisman || Sultry Doll || Dragon Tear || Crystal || Fenghuang Feather || Ancient Amulet || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth
10
Sword Soldier Only Mission

You can do this after completing all the Thieves' Mine missions
You can only play this mission with a squad of ONLY Sword soldiers
Objective: Defeat the mini-boss
Difficulty: ****** || Reward: 3 Ryo
Obtainable Items:
Dragon Eye || Murderer's Handcuffs || Folding Fan || Bloodstained Cloth || Indigo Stone || Golden Stamp || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder || Gold Metal Powder
11
Spear Soldier Only Mission

You can do this after completing mission 10
You can only play this mission with a squad of ONLY Spear soldiers
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
God Slaying Talisman || Sultry Doll || Dragon Tear || Crystal || Fenghuang Feather || Ancient Amulet || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder
12
Gun Soldier Only Mission

You can do this after completing mission 11
You can only play this mission with a squad of ONLY Gun soldiers
Objective: Defeat the mini-boss
Difficulty: ******** || Reward: 3 Ryo
Obtainable Items:
Golden Inro || Samurai's Hair String || Straw Figure || Water God Stone || Flint || Black Obi || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder || Gold Metal Powder
13
Defeat the Sword Attack Force

You can do this after completing mission 6
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Crimson Jewel || Golden Stamp || Sultry Doll || Dragon Tear || Crystal || Fenghuang Feather || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth
14
Defeat the Spear Attack Force

You can do this after completing mission 6
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Dragon Eye || Straw Figure || Water God Stone || Flint || Black Obi || Murderer's Handcuffs || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder
15
Defeat the Gun Attack Force
You can do this after completing mission 6
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Snake Skin || Black Obi || Murderer's Handcuffs || Folding Fan || Bloodstained Cloth || Indigo Stone || Large Gold Nugget || Platinum Grain || Platinum Lump || Rainbow-Coloured Fragment || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder || Gold Metal Powder
16
Defeat the Strong Warrior Attack Force
You can do this after completing mission 6
Objective: Defeat the mini-boss
Difficulty: ******* || Reward: 3 Ryo
Obtainable Items:
Golden Inro || Sultry Doll || Dragon Tear || Crystal || Fenghuang Feather || Ancient Amulet || Rainbow-Coloured Fragment || Small Clockwork || Handmade Device || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch || Sacred Tree Wood || Vermilion Cloth || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder || Gold Metal Powder
17
Defeat the Three Warriors
You can do this after completing mission 12
Objective: Defeat the mini-bosses
Difficulty: ******** || Reward: 5 Ryo
Obtainable Items:
Eyepatch with a Snake Design || Golden Inro || Snake Skin || Murderer's Handcuffs || Folding Fan || Bloodstained Cloth || Indigo Stone || Golden Stamp || Broken Compass || Precision Machine || Driftwood Piece || 1000 Year Old Tree Branch
18
Defeat the Four Divine Kings
You can do this after completing mission 17
Objective: Defeat the mini-bosses
Difficulty: ******** || Reward: 5 Ryo
Obtainable Items:
Haori with Torn Sleeves || Crimson Jewel || God Slaying Talisman || Black Obi || Murderer's Handcuffs || Folding Fan || Bloodstained Cloth || Indigo Stone || Beautiful Silk || European Cloth || Rainbow-Coloured Fabric || Silver Metal Powder
19
Defeat the Five Tiger Generals
You can do this after completing mission 18
Objective: Defeat the mini-bosses
Difficulty: ********* || Reward: 5 Ryo
Obtainable Items:
Dragon Eye || Dragon Whisker || Dragon Fang || Samurai's Hair String || Straw Figure || Water God Stone || Flint || Black Obi || Platinum Lump || Rainbow-Coloured Fragment || Precision Machine || Driftwood Piece
20
Defeat Toyotomi Hidebu

You can do this after completing missions 1-19
Objective: Defeat Toyotomi Hidebu
Difficulty: ********** || Reward: 20 Ryo
Obtainable Items:
Crimson Jewel || Dragon Eye || Golden Inro || Snake Skin || God Slaying Talisman || Dragon Whisker || Dragon Fang || Inaka School Catalogue || Eyepatch with a Snake Design || Haori with Torn Sleeves